Determinants of glomerular permselectivity: Insights derived from observations in vivo
نویسندگان
چکیده
منابع مشابه
Analysis of Glomerular Permselectivity in the Rat Using
Changes in glomerular permselectivity are the physiological basis for proteinuria, which typically accompanies chronic kidney disease. Traditionally changes in the sizerestrictive properties of the glomerular barrier have been quantified by measuring the fractional clearance ( ) of exogenous infused dextrans and interpreting the results using the hindered transport theory for uncharged, solid s...
متن کاملPermselectivity of the glomerular wall examined with iron compound tracer.
Rat kidney endothelial cell morphology was examined after introducing iron colloid particles of positive or negative charge to investigate the relationship between the electric charge and permeation through the glomerular capillary. The kidneys were first perfused with Hanks’ solution through the renal arteries and then with iron colloid particles of positive or negative charge. The iron colloi...
متن کاملDirect antiGBM antibody induced alterations in glomerular permselectivity.
The glomerular fixation of anti-glomerular-basement-membrane (antiGBM) antibody is associated with complement activation, neutrophil accumulation, and renal injury. This injury manifests both as an increase in the rate of urinary protein excretion and altered renal hemodynamic characteristics. We have utilized an isolated perfused kidney system (IPK) to assess the capacity of antiGBM antibody t...
متن کاملDifferentiation of Glomerular from Non-Glomerular Hematuria by Three Different Me-thods of Microscopic Examinations of Erythrocytes in Urine
Background: Morphological examinations of urinary erythrocytes can be of diagnostic value in initial evaluation of hematuria. Dysmorphic urinary red blood cells are known to indicate a glomerular origin of bleeding. We examined the clinical usefulness of this test in a population complained of hematuria by use of three different methods: light microscopy, phase contrast microscopy, and Wright s...
متن کاملthe role of russia in transmission of energy from central asia and caucuses to european union
پس ازفروپاشی شوروی،رشد منابع نفت و گاز، آسیای میانه و قفقاز را در یک بازی ژئوپلتیکی انرژی قرار داده است. با در نظر گرفتن این منابع هیدروکربنی، این منطقه به یک میدانجنگ و رقابت تجاری برای بازی های ژئوپلتیکی قدرت های بزرگ جهانی تبدیل شده است. روسیه منطقه را به عنوان حیات خلوت خود تلقی نموده و علاقمند به حفظ حضورش می باشد تا همانند گذشته گاز طبیعی را به وسیله خط لوله مرکزی دریافت و به عنوان یک واس...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Kidney International
سال: 1977
ISSN: 0085-2538
DOI: 10.1038/ki.1977.107